Prayer request for all over the world will be answer with United in Prayers
Prayer request for Week of November 18, 2007 PDF Print E-mail

Thank you to all prayed that science will continue to investigate and develop alternatives to human embryo stem cells research.

Scientists say they have succeeded in genetically reprogramming skin tissue to create powerful “master” cells that are as versatile as the stem cells from human embryos — and which can help in the development of treatments for diseases such as Parkinson’s and diabetes.

The reprogrammed cells have the potential to form any kind of human tissue, according to two separate research teams, from Japan and the United States.

The results allow for a new approach to stem-cell therapy that skirts some of the ethical and practical problems that have limited its progress to date, such as the destruction of human embryos. Once perfected, the technique would allow scientists to take skin cells from patients with conditions such as diabetes and spinal paralysis, and turn them into stem cells. These could then be grown into “spare part” tissue, which could be transplanted without fear of rejection by the body’s immune system because the cells are genetically the patient’s own.

The method requires neither cloning nor the destruction of human embryos, regarded as immoral by many religious groups. It also gets round the shortage of human eggs and surplus embryos, which has held up research into stem cells and therapeutic cloning.

Both teams of scientists said, however, that the advance in no way implied that embryonic stem cell research was outdated or unethical, and they insisted that the older method must proceed in parallel to the new approach to give the best chance of progress. The reprogramming technique could not have been developed without extensive study of embryonic stem cells, and the so-called induced pluripotent stem cells it produces are slightly different from the real thing.

Professor Jamie Thomson, of the University of Wisconsin-Madison, who led one of the studies, said: “It is hardly time to discontinue embryonic stem cell research.”

The new type of stem cells were also made by manipulating genes with a virus that might induce mutations that could cause cancer and one of the altered genes is known to be implicated in some tumours. That means that more research will be needed before the cells can be used for therapy, but they could have immediate applications for investigating genetic disease.

Cells could be taken from patients with conditions such as Parkinson’s or motor neuron disease, then reprogrammed and grown into nerve cells for studying the progress of the disorders and testing new drugs.

Embryonic stem cells have excited scientists since they were first derived from human embryos by Professor Thomson in 1998, because they have the potential to form any tissue in the human body. They could thus be used to treat diseases in which cells become damaged or die, and if produced from cloned embryos they could be precisely matched to individuals.

 
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